Expertise

We have specific expertise in design and analysis of animal experiments, all phases of human clinical trials, disease incidence studies, clinical registries, rehabilitation and allied health studies, inter- and intra-rater reliability studies, meta-analyses, studies with ordinal, survival, or count outcomes, imaging studies, and health services research studies including process of care models, systems modelling, optimization and simulation.
We collaborate on, and provide advice and consulting services regarding:

Statistical and design aspects of:

  • Protocol development
  • Ethics application development
  • External bodies funding application development
  • Presentations and writing up the results

Study design:

  • Refinement of research hypotheses and questions
  • Selection of appropriate outcome measures and measurement scales, stratification, and blocking mechanisms
  • Questionnaire design
  • Effect size elicitation from the literature through meta-analysis
  • Power analysis and sample size calculations
  • Creation of randomisation schedules

Statistical analysis:

  • Analysis planning
  • Statistical analysis
  • Programming of tables, listings and figures
  • Analysis services to Data Safety Monitoring Boards, including conducting interim analyses and statistical monitoring

Data management:

  • Specification and validation of data structures and data handling procedures
  • Design and maintenance of databases, electronic case report forms, and data entry screens
  • Validation/Consistency check programming
  • Development and Validation of Data Management Plans
  • Data capture and cleaning
  • Creating data sets from scanned forms